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CLINICAL STUDIES

Computer-assisted cryocompression therapy reduces pain and enhances rapid recovery of range of motion after unicompartmental knee arthroplasty

Received: March 01, 2025
Accepted: March 10, 2025
Published: March 21, 2025

Computer-assisted cryocompression therapy reduces pain and enhances rapid recovery of range of motion after unicompartmental knee arthroplasty

Stefano Petrillo1, Matteo Marullo1, Guido Bandettini1, Edoardo Bertello2, Biagio Zampogna3,4,5, Laura Mangiavini6,7, Giuseppe M. Peretti6,7, Paolo Perazzo8, Sergio Romagnoli1, Riccardo Giorgino6*
1.Department of Joint Replacement, IRCCS Ospedale Galeazzi San’Ambrogio, Milan, Italy
2.Residency Program in Orthopaedics and Traumatology, University of Milan, Milan, Italy
3.Department of Orthopedic and Trauma Surgery, Università Campus Bio-Medico di Roma, Roma, Italy.
4.Research Unit of Orthopedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio- Medico, Rome, Italy.
5.BIOMORF Department, Biomedical, Dental, Morphological and Functional Images, University of Messina, A.O.U. Policlinico “G.Martino”, Messina, Italy
6.IRCCS Ospedale Galeazzi Sant’Ambrogio, 20157 Milan, Italy
7.Department of Biomedical Sciences for Health, University of Milan, 20122 Milan, Italy
8.Intensive care Unit, IRCCS Ospedale Galeazzi Sant’Ambrogio, Milan, Italy


Abstract

Background/Objectives

Knee prosthetic surgery is highly effective for advanced osteoarthritis, improving quality of life. Postoperative pain management and rapid knee range of motion recovery are crucial for avoiding readmissions. Cryocompression therapy reduces pain, swelling, and opioid use. Computer-assisted cryocompression therapy (CA- CCT) shows promise over traditional ice packs in enhancing recovery after unicompartmental knee arthroplasty. This study aims to compare cryocompression therapy and ice pack therapy (IPT) in unicompartmental knee arthroplasty for improved recovery and outcomes. Methods: A single-center retrospective comparative study analyzed the efficacy of CA-CCT versus IPT in 35 patients who underwent medial UKA, matched 1:1 with a control group (35 patients). Both groups were similar in terms of sex, age, body mass index, and preoperative hemoglobin values. All patients underwent spinal anesthesia, used intra-articular drains removed after 6 hours, and followed a standardized analgesic protocol. Statistical analysis was performed to evaluate differences in ROM, visual analogue scale for pain, blood loss, and decrease in Hb. Significance was set at P < 0.05. Results: No complications, readmissions, or prolonged hospital stays were reported, with a mean stay of 2 days for both groups. Statistically significant improvements in ROM (P < 0.00001) and VAS scores (P < 0.00001) were observed in the CA-CCT group at 6, 24 and 48 hours post- surgery compared to the IPT group. Blood loss and Hb decrease were similar between groups (P = 0.6 for blood loss and P = 0.8 for Hb decrease). Conclusions: CA-CCT significantly improves postoperative pain control and knee function compared to IPT after UKA. Future prospective studies are needed to validate these results and assess the cost-effectiveness of CA-CCT.